Anti-Cleaved-MMP20-Tyr108 antibody (107-108) (STJA0005891)

Name: Anti-Cleaved-MMP20-Tyr108 antibody (107-108) (STJA0005891)
SKU: STJA0005891
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthesized peptide derived from human MMP20 (Cleaved-Tyr108)

STJA0005891

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Short Description	Rabbit polyclonal anti-Cleaved-Matrix metalloproteinase-20-Tyr108 (107-108) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Dilution Range	WB 1:500-2000 IHC-p 1:50-300
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	MMP20
Gene ID	9313
Uniprot ID	MMP20_HUMAN
Immunogen	Synthesized peptide derived from human MMP20 (Cleaved-Tyr108)
Immunogen Region	107-108
Specificity	This antibody detects endogenous levels of Human, Mouse, Rat MMP20 (Cleaved-Tyr108, protein was cleaved amino acid sequence between 107-108 )

Tissue Specificity	Expressed specifically in the enamel organ.
Post Translational Modifications	Autoactivates at least at the 107-Asn-\|-Tyr-108 site.
Function	Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-\|-Phe-361' site.
Protein Name	Matrix Metalloproteinase-20 Mmp-20 Enamel Metalloproteinase Enamelysin
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-2022090
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Matrix Metalloproteinase-20 antibody Anti-Mmp-20 antibody Anti-Enamel Metalloproteinase antibody Anti-Enamelysin antibody Anti-MMP20 antibody

Information sourced from Uniprot.org