Anti-Cleaved-ITIH3-Asp651 antibody (651-652) (STJA0005880)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ITIH3 (Cleaved-Asp651)
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Inter-alpha-trypsin inhibitor heavy chain H3-Asp651 (651-652) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ITIH3 |
| Gene ID | 3699 |
| Uniprot ID | ITIH3_HUMAN |
| Immunogen | Synthesized peptide derived from human ITIH3 (Cleaved-Asp651) |
| Immunogen Region | 651-652 |
| Specificity | This antibody detects endogenous levels of Human, Mouse, Rat ITIH3 (Cleaved-Asp651, protein was cleaved amino acid sequence between 651-652 ) |
Additional Info
| Post Translational Modifications | Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. |
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. |
| Protein Name | Inter-Alpha-Trypsin Inhibitor Heavy Chain H3Iti Heavy Chain H3Iti-Hc3Inter-Alpha-Inhibitor Heavy Chain 3Serum-Derived Hyaluronan-Associated ProteinShap |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Inter-Alpha-Trypsin Inhibitor Heavy Chain H3 antibodyAnti-Iti Heavy Chain H3 antibodyAnti-Iti-Hc3 antibodyAnti-Inter-Alpha-Inhibitor Heavy Chain 3 antibodyAnti-Serum-Derived Hyaluronan-Associated Protein antibodyAnti-Shap antibodyAnti-ITIH3 antibody |
Information sourced from Uniprot.org