Anti-Cleaved-GGT7-T472 antibody (423-472 aa) (STJ90085)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Gamma-glutamyltransferase 4 at the amino acid range 423-472
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Glutathione hydrolase 7-T472 (423-472 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GGT7 |
| Gene ID | 2686 |
| Uniprot ID | GGT7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Gamma-glutamyltransferase 4 at the amino acid range 423-472 |
| Immunogen Region | 423-472 aa |
| Specificity | Cleaved-GGT4 HC (T472) Polyclonal Antibody detects endogenous levels of fragment of activated GGT4 HC protein resulting from cleavage adjacent to T472. |
Additional Info
| Post Translational Modifications | Cleaved by autocatalysis into a large and a small subunit and the autocatalytic cleavage is essential to the functional activation of the enzyme. |
| Function | Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors. |
| Protein Name | Glutathione Hydrolase 7Gamma-Glutamyltransferase 7Ggt 7Gamma-Glutamyltransferase-Like 3Gamma-Glutamyltransferase-Like 5Gamma-Glutamyltranspeptidase 7 Cleaved Into - Glutathione Hydrolase 7 Heavy Chain - Glutathione Hydrolase 7 Light Chain |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-5423646Reactome: R-HSA-9753281 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Glutathione Hydrolase 7 antibodyAnti-Gamma-Glutamyltransferase 7 antibodyAnti-Ggt 7 antibodyAnti-Gamma-Glutamyltransferase-Like 3 antibodyAnti-Gamma-Glutamyltransferase-Like 5 antibodyAnti-Gamma-Glutamyltranspeptidase 7 Cleaved Into - Glutathione Hydrolase 7 Heavy Chain - Glutathione Hydrolase 7 Light Chain antibodyAnti-GGT7 antibodyAnti-GGTL3 antibodyAnti-GGTL5 antibody |
Information sourced from Uniprot.org