Anti-Cleaved-EPX-Val251, Heavy Chain antibody (250-251) (STJA0005857)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Eosinophil peroxidase (heavy chain, Cleaved-Val251)
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Eosinophil peroxidase-Val251, Heavy Chain (250-251) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EPX |
| Gene ID | 8288 |
| Uniprot ID | PERE_HUMAN |
| Immunogen | Synthesized peptide derived from human Eosinophil peroxidase (heavy chain, Cleaved-Val251) |
| Immunogen Region | 250-251 |
| Specificity | This antibody detects endogenous levels of Human, Mouse, Rat Eosinophil peroxidase (heavy chain, Cleaved-Val251, protein was cleaved amino acid sequence between 250-251 ) |
Additional Info
| Function | Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. |
| Protein Name | Eosinophil PeroxidaseEpo Cleaved Into - Eosinophil Peroxidase Light Chain - Eosinophil Peroxidase Heavy Chain |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleCytoplasmic Granules Of Eosinophils |
| Alternative Antibody Names | Anti-Eosinophil Peroxidase antibodyAnti-Epo Cleaved Into - Eosinophil Peroxidase Light Chain - Eosinophil Peroxidase Heavy Chain antibodyAnti-EPX antibodyAnti-EPER antibodyAnti-EPO antibodyAnti-EPP antibody |
Information sourced from Uniprot.org