Anti-Cleaved-COL11A1-Ala1563 antibody (1563-1564) (STJA0005844)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Collagen XI Alpha 1 (Cleaved-Ala1563)
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Collagen alpha-1XI chain-Ala1563 (1563-1564) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | COL11A1 |
| Gene ID | 1301 |
| Uniprot ID | COBA1_HUMAN |
| Immunogen | Synthesized peptide derived from human Collagen XI Alpha 1 (Cleaved-Ala1563) |
| Immunogen Region | 1563-1564 |
| Specificity | This antibody detects endogenous levels of Human, Mouse Collagen XI Alpha 1 (Cleaved-Ala1563, protein was cleaved amino acid sequence between 1563-1564 ) |
Additional Info
| Tissue Specificity | Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon. |
| Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. N-glycosylated. |
| Function | May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. |
| Protein Name | Collagen Alpha-1(Xi Chain |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1650814Reactome: R-HSA-2022090Reactome: R-HSA-3000171Reactome: R-HSA-8874081Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Xi Chain antibodyAnti-COL11A1 antibodyAnti-COLL6 antibody |
Information sourced from Uniprot.org