Anti-CLDN6 antibody (121-220) (STJ11103319)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CLDN6 (121-220) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLDN6 |
| Gene ID | 9074 |
| Uniprot ID | CLD6_HUMAN |
| Immunogen Region | 121-220 |
| Immunogen Sequence | SGIVFVISGVLTLIPVCWTA HAIIRDFYNPLVAEAQKREL GASLYLGWAASGLLLLGGGL LCCTCPSGGSQGPSHYMARY STSAPAISRGPSEYPTKNYV |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 121-220 of human Claudin 6 (NP_067018.2). |
Additional Info
| Tissue Specificity | Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines. |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space. (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells. |
| Protein Name | Claudin-6Skullin |
| Database Links | Reactome: R-HSA-420029 |
| Cellular Localisation | Cell JunctionTight JunctionCell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Claudin-6 antibodyAnti-Skullin antibodyAnti-CLDN6 antibodyAnti-UNQ757 antibodyAnti-PRO1488 antibody |
Information sourced from Uniprot.org