Anti-CK-MB antibody [7502] (STJ400040)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenNot determined
STJ400040
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General Information

Short DescriptionMouse monoclonal anti-CK-MB for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsFIA
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID7502
IsotypeIgG1
ConjugationUnconjugated
Concentration5.0 mg/ml (+/-10 %)
Formulation37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Storage InstructionStore at 2–8 °C, and do not freeze.

Target Information

ImmunogenNot determined
SpecificityAntibody recognizes human creatine kinase MB isoenzyme. CK-BB isoenzyme

Additional Info

Background Creatine kinase (CK) , also known as creatine phosphokinase (CPK) or phospho-creatine kinase is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. CK is often determined routinely in emergency patients. In addition, it is determined specifically in patients with chest pain and if acute renal failure is suspected. Elevation of CK is an indication of damage to muscle. It is therefore indicative of injury, rhabdomyolysis, myocardial infarction, muscular dystrophy, myositis, myocarditis, malignant hyperthermia, and neuroleptic malignant syndrome. Lowered CK can be an indication of alcoholic liver disease and rheumatoid arthritis.

Information sourced from Uniprot.org

Citations

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