Anti-CISD2 antibody (31-80 aa) (STJ192586)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 31-80
General Information
| Short Description | Rabbit polyclonal anti-CDGSH iron-sulfur domain-containing protein 2 (31-80 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CISD2 |
| Gene ID | 493856 |
| Uniprot ID | CISD2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 31-80 |
| Immunogen Region | 31-80 aa |
| Specificity | CISD2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. |
| Protein Name | Cdgsh Iron-Sulfur Domain-Containing Protein 2Endoplasmic Reticulum Intermembrane Small ProteinMitoneet-Related 1 ProteinMiner1Nutrient-Deprivation Autophagy Factor-1Naf-1 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinMitochondrion Outer MembraneIt Mainly Localizes To The Endoplasmic ReticulumHoweverExperiments In Mouse Showed That It Mainly Localizes To The Mitochondrion Outer Membrane |
| Alternative Antibody Names | Anti-Cdgsh Iron-Sulfur Domain-Containing Protein 2 antibodyAnti-Endoplasmic Reticulum Intermembrane Small Protein antibodyAnti-Mitoneet-Related 1 Protein antibodyAnti-Miner1 antibodyAnti-Nutrient-Deprivation Autophagy Factor-1 antibodyAnti-Naf-1 antibodyAnti-CISD2 antibodyAnti-CDGSH2 antibodyAnti-ERIS antibodyAnti-ZCD2 antibody |
Information sourced from Uniprot.org