Anti-CHST15 antibody (440-520 aa) (STJ192333)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 440-520
General Information
| Short Description | Rabbit polyclonal anti-Carbohydrate sulfotransferase 15 (440-520 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHST15 |
| Gene ID | 51363 |
| Uniprot ID | CHSTF_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 440-520 |
| Immunogen Region | 440-520 aa |
| Specificity | CHSTF Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression.however such results are unclear in vivo. |
| Protein Name | Carbohydrate Sulfotransferase 15B-Cell Rag-Associated Gene ProteinHbragN-Acetylgalactosamine 4-Sulfate 6-O-SulfotransferaseGalnac4s-6st |
| Database Links | Reactome: R-HSA-2022870 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinA Small Fraction May Also Be Present At The Cell SurfaceWhere It Acts As A B-Cell Receptor |
| Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 15 antibodyAnti-B-Cell Rag-Associated Gene Protein antibodyAnti-Hbrag antibodyAnti-N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase antibodyAnti-Galnac4s-6st antibodyAnti-CHST15 antibodyAnti-BRAG antibodyAnti-GALNAC4S6ST antibodyAnti-KIAA0598 antibody |
Information sourced from Uniprot.org