Anti-Chromogranin B antibody (550-650) [S0MR] (STJ11103520)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Chromogranin B (550-650) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S0MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHGB |
| Gene ID | 1114 |
| Uniprot ID | SCG1_HUMAN |
| Immunogen Region | 550-650 |
| Immunogen Sequence | EEENELTLNEKNFFPEYNYD WWEKKPFSEDVNWGYEKRNL ARVPKLDLKRQYDRVAQLDQ LLHYRKKSAEFPDFYDSEEP VSTHQEAENEKDRADQTVLT E |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human Chromogranin B (P05060). |
Additional Info
| Tissue Specificity | Detected in cerebrospinal fluid and urine (at protein level). Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver. |
| Post Translational Modifications | Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues. O-glycosylated. |
| Function | Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. |
| Protein Name | Secretogranin-1Chromogranin-BCgbSecretogranin ISgi Cleaved Into - Pe-11 - Gawk Peptide - Ccb Peptide |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedNeuroendocrine And Endocrine Secretory Granules |
| Alternative Antibody Names | Anti-Secretogranin-1 antibodyAnti-Chromogranin-B antibodyAnti-Cgb antibodyAnti-Secretogranin I antibodyAnti-Sgi Cleaved Into - Pe-11 - Gawk Peptide - Ccb Peptide antibodyAnti-CHGB antibodyAnti-SCG1 antibody |
Information sourced from Uniprot.org