Anti-CHRNE antibody (21-239) (STJ112097)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CHRNE (21-239) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHRNE |
| Gene ID | 1145 |
| Uniprot ID | ACHE_HUMAN |
| Immunogen Region | 21-239 |
| Immunogen Sequence | KNEELRLYHHLFNNYDPGSR PVREPEDTVTISLKVTLTNL ISLNEKEETLTTSVWIGIDW QDYRLNYSKDDFGGIETLRV PSELVWLPEIVLENNIDGQF GVAYDANVLVYEGGSVTWLP PAIYRSVCAVEVTYFPFDWQ NCSLIFRSQTYNAEEVEFTF AVDNDGKTINKIDIDTEAYT ENGEWAIDFCPGVIRRHHGG ATDGPGETDVIYSLIIRRK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CHRNE (NP_000071.1). |
Additional Info
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Protein Name | Acetylcholine Receptor Subunit Epsilon |
| Database Links | Reactome: R-HSA-629587 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Acetylcholine Receptor Subunit Epsilon antibodyAnti-CHRNE antibodyAnti-ACHRE antibody |
Information sourced from Uniprot.org