Anti-CHRM3 antibody (390-590) (STJ29860)

Name: Anti-CHRM3 antibody (390-590) (STJ29860)
SKU: STJ29860
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ29860

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Short Description	Rabbit polyclonal CHRM3 (390-590) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:5000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CHRM3
Gene ID	1131
Uniprot ID	ACM3_HUMAN
Immunogen Region	390-590
Immunogen Sequence	QVPEEELGMVDLERKADKLQ AQKSVDDGGSFPKSFSKLPI QLESAVDTAKTSDVNSSVGK STATLPLSFKEATLAKRFAL KTRSQI
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 390-475 of human CHRM3 (NP_000731.1).

Function	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Protein Name	Muscarinic Acetylcholine Receptor M3
Database Links	Reactome: R-HSA-390648 Reactome: R-HSA-399997 Reactome: R-HSA-416476
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Postsynaptic Cell Membrane Basolateral Cell Membrane Endoplasmic Reticulum Membrane Colocalizes With Tmem147 In The Endoplasmic Reticulum (Er) Membrane Tmem147 Impairs Its Trafficking To The Cell Membrane Leading To Its Retention In The Er Membrane
Alternative Antibody Names	Anti-Muscarinic Acetylcholine Receptor M3 antibody Anti-CHRM3 antibody

Information sourced from Uniprot.org