Anti-CHN2 antibody (STJA0008963)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Chimaerin 2
General Information
| Short Description | Rabbit polyclonal anti-Beta-chimaerin for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHN2 |
| Gene ID | 1124 |
| Uniprot ID | CHIO_HUMAN |
| Immunogen | Synthesized peptide derived from human Chimaerin 2 |
| Specificity | This antibody detects endogenous levels of Chimaerin 2 at Human, Mouse, Rat |
Additional Info
| Function | GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors. |
| Protein Name | Beta-ChimaerinBeta-ChimerinRho Gtpase-Activating Protein 3 |
| Database Links | Reactome: R-HSA-9013149 |
| Cellular Localisation | MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Beta-Chimaerin antibodyAnti-Beta-Chimerin antibodyAnti-Rho Gtpase-Activating Protein 3 antibodyAnti-CHN2 antibodyAnti-ARHGAP3 antibodyAnti-BCH antibody |
Information sourced from Uniprot.org