Anti-CHN2 antibody (150-180) {Biotin} (STJ500530)

Name: Anti-CHN2 antibody (150-180) {Biotin} (STJ500530)
SKU: STJ500530-100
Price: 686.55 USD
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationBiotin

IsotypeIgG

ImmunogenSynthetic peptide taken within amino acid region 150-180 on beta 2-chimaerin protein.

STJ500530-100

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Short Description	Rabbit polyclonal antibody anti-CHN2 (150-180) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IHC/IP/WB
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Biotin
Concentration	0.68-0.71 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	CHN2
Gene ID	1124
Uniprot ID	CHIO_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 150-180 on beta 2-chimaerin protein.
Immunogen Region	150-180

Tissue Specificity	Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
Function	GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
Protein Name	Beta-Chimaerin Beta-Chimerin Rho Gtpase-Activating Protein 3
Database Links	Reactome: R-HSA-9013149
Cellular Localisation	Membrane Peripheral Membrane Protein
Alternative Antibody Names	Anti-Beta-Chimaerin antibody Anti-Beta-Chimerin antibody Anti-Rho Gtpase-Activating Protein 3 antibody Anti-CHN2 antibody Anti-ARHGAP3 antibody Anti-BCH antibody

Information sourced from Uniprot.org