| Host: |
Goat |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse/Monkey/Canine |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Choroideremia (Rab escort protein 2) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: |
This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: |
3 mg/ml |
| Dilution Range: |
WB 1:500-1:5000 |
| Gene Symbol: |
CHML |
| Gene ID: |
1122 |
| Uniprot ID: |
RAE2_HUMAN |
| Accession Number: |
ENSG00000203668 |
| Specificity: |
Detects endogenous REP2 by Western blot. This Ab is specific for REP2, it does not cross-react with REP1. |
| Immunogen: |
Purified recombinant human TNF alpha produced in E. coli. |
| Function | Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. |
| Protein Name | Rab Proteins Geranylgeranyltransferase Component A 2Choroideremia-Like ProteinRab Escort Protein 2Rep-2 |
| Database Links | Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Rab Proteins Geranylgeranyltransferase Component A 2 antibodyAnti-Choroideremia-Like Protein antibodyAnti-Rab Escort Protein 2 antibodyAnti-Rep-2 antibodyAnti-CHML antibodyAnti-REP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
