Anti-CHML antibody (1-100 aa) (STJ11106577)

Name: Anti-CHML antibody (1-100 aa) (STJ11106577)
SKU: STJ11106577
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11106577

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Short Description	Rabbit polyclonal CHML (1-100 aa) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CHML
Gene ID	1122
Uniprot ID	RAE2_HUMAN
Immunogen Region	1-100 aa
Immunogen Sequence	MADNLPTEFDVVIIGTGLPE SILAAACSRSGQRVLHIDSR SYYGGNWASFSFSGLLSWLK EYQQNNDIGEESTVVWQDLI HETEEAITLRKKDETIQHTE
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CHML (NP_001812.2).

Function	Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Protein Name	Rab Proteins Geranylgeranyltransferase Component A 2 Choroideremia-Like Protein Rab Escort Protein 2 Rep-2
Database Links	Reactome: R-HSA-8873719 Reactome: R-HSA-8876198
Cellular Localisation	Cytoplasm Cytosol
Alternative Antibody Names	Anti-Rab Proteins Geranylgeranyltransferase Component A 2 antibody Anti-Choroideremia-Like Protein antibody Anti-Rab Escort Protein 2 antibody Anti-Rep-2 antibody Anti-CHML antibody Anti-REP2 antibody

Information sourced from Uniprot.org