| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CHIT1 (409-423) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx 48kDa band observed in lysates of cell line Daudi (calculated MW of 51.7kDa according to NP_003456.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CHIT1 |
| Gene ID: | 1118 |
| Uniprot ID: | CHIT1_HUMAN |
| Immunogen Region: | 409-423 |
| Accession Number: | NP_003456.1 |
| Immunogen Sequence: | EHGPSPGQDTFCQGK |
| Function | Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. |
| Protein Name | Chitotriosidase-1Chitinase-1 |
| Database Links | Reactome: R-HSA-189085Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedLysosomeA Small Proportion Is Lysosomal |
| Alternative Antibody Names | Anti-Chitotriosidase-1 antibodyAnti-Chitinase-1 antibodyAnti-CHIT1 antibody |
Information sourced from Uniprot.org
