Anti-CHD4 IP antibody [SAA0262] (STJA0018777)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Chromodomain-Helicase-Dna-Binding Protein 4 antibody for use in ELISA, IF and IP in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IF/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0262 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | CHD4 |
| Gene ID | 1108 |
| Uniprot ID | CHD4_HUMAN |
Additional Info
| Function | ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis. |
| Protein Name | Chromodomain-Helicase-Dna-Binding Protein 4Chd-4Atp-Dependent Helicase Chd4Mi-2 Autoantigen 218 Kda ProteinMi2-Beta |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427389Reactome: R-HSA-6804758Reactome: R-HSA-73762Reactome: R-HSA-8943724Reactome: R-HSA-9031628Reactome: R-HSA-9679191Reactome: R-HSA-9843940Reactome: R-HSA-9844594Reactome: R-HSA-9845323 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeAssociates With Centrosomes In InterphaseLocalizes To Sites Of Dna Damage In A Manner Dependent On Zmynd8 And Znf687 |
| Alternative Antibody Names | Anti-Chromodomain-Helicase-Dna-Binding Protein 4 antibodyAnti-Chd-4 antibodyAnti-Atp-Dependent Helicase Chd4 antibodyAnti-Mi-2 Autoantigen 218 Kda Protein antibodyAnti-Mi2-Beta antibodyAnti-CHD4 antibody |
Information sourced from Uniprot.org