Anti-CHD2 antibody (1-223) (STJ28168)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CHD2 (1-223) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHD2 |
| Gene ID | 1106 |
| Uniprot ID | CHD2_HUMAN |
| Immunogen Region | 1-223 |
| Immunogen Sequence | MMRNKDKSQEEDSSLHSNAS SHSASEEASGSDSGSQSESE QGSDPGSGHGSESNSSSESS ESQSESESESAGSKSQPVLP EAKEKPASKKERIADVKKMW EEYPDVYGVRRSNRSRQEPS RFNIKEEASSGSESGSPKRR GQRQLKKQEKWKQEPSEDEQ EQGTSAESEPEQKKVKARRP VPRRTVPKPRVKKQPKTQRG KRKKQDSSDEDDDDDEAPKR QTR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human CHD2 (NP_001036037.1). |
Additional Info
| Function | ATP-dependent chromatin-remodeling factor that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression. |
| Protein Name | Chromodomain-Helicase-Dna-Binding Protein 2Chd-2Atp-Dependent Helicase Chd2 |
| Database Links | |
| Cellular Localisation | NucleusBinds To Myogenic Gene Promoters |
| Alternative Antibody Names | Anti-Chromodomain-Helicase-Dna-Binding Protein 2 antibodyAnti-Chd-2 antibodyAnti-Atp-Dependent Helicase Chd2 antibodyAnti-CHD2 antibody |
Information sourced from Uniprot.org