Anti-CEP43 antibody (300-399) [S4164RM] (STJ11104164)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11104164
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General Information

Short DescriptionRabbit monoclonal Centrosomal Protein 43 (300-399) antibody for use in ELISA, WB, IF and ICC in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsELISA/WB/IF/ICC
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS4164RM
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:1000
IF/ICC:1:50-1:200
FormulationPBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCEP43
Gene ID11116
Uniprot IDCEP43_HUMAN
Immunogen Region300-399
Immunogen SequencePSLKDSESKRGNTVLKDLKL ISDKIGSLGLGTGEDDDYVD DFNSTSHRSEKSEISIGEEI EEDLSVEIDDINTSDKLDDL TQDLTVSQLSDVADYLEDVA
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 300-399 of human CEP43 (NP_008976.1).

Additional Info

Tissue Specificity Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas.
Function Required for anchoring microtubules to the centrosomes. Required for ciliation.
Protein Name Centrosomal Protein 43
Fgfr1 Oncogene Partner
Database Links Reactome: R-HSA-1839117
Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-5655302
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Cilium Basal Body
Associated With Gamma-Tubulin
Localizes On Both Mother And Daughter Centrioles
Localizes To An Axial Position On The Mother Centriole
Localizes To The Distal End Of The Centriole Partly On The Subdistal Appendage Region
Alternative Antibody Names Anti-Centrosomal Protein 43 antibody
Anti-Fgfr1 Oncogene Partner antibody
Anti-CEP43 antibody
Anti-FGFR1OP antibody
Anti-FOP antibody

Information sourced from Uniprot.org

Citations

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