| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CENTG3/MRIP1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave an approx 45kDa band in Human Brain and Human Liver lysates at 1ug/ml. This band was successfully blocked by incubation with the immunising peptide. Please |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | AGAP3 |
| Gene ID: | 116988 |
| Uniprot ID: | AGAP3_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_114152.3 |
| Immunogen Sequence: | NPSAELHRSPSLL |
| Function | GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway. |
| Protein Name | Arf-Gap With Gtpase - Ank Repeat And Ph Domain-Containing Protein 3Agap-3Cram-Associated GtpaseCragCentaurin-Gamma-3Cnt-G3Mr1-Interacting ProteinMrip-1 |
| Cellular Localisation | CytoplasmIn Cells Upon Oxidative Stress Or In Brains Of Machado-Joseph Disease PatientsTranslocates To Pml Nuclear Bodies |
| Alternative Antibody Names | Anti-Arf-Gap With Gtpase - Ank Repeat And Ph Domain-Containing Protein 3 antibodyAnti-Agap-3 antibodyAnti-Cram-Associated Gtpase antibodyAnti-Crag antibodyAnti-Centaurin-Gamma-3 antibodyAnti-Cnt-G3 antibodyAnti-Mr1-Interacting Protein antibodyAnti-Mrip-1 antibodyAnti-AGAP3 antibodyAnti-CENTG3 antibody |
Information sourced from Uniprot.org