| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-CENTD2/ARAP1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
ARAP1 |
| Gene ID: |
116985 |
| Uniprot ID: |
ARAP1_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_056057.2; NP_001035207.1; NP_001128662.1 |
| Specificity: |
This antibody is expected to recognise isoform a (NP_056057.2) , isoform c (NP_001035207.1) and isoform d (NP_001128662.1). |
| Immunogen Sequence: |
AFTADPLSLLRNV |
| Function | Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5. |
| Protein Name | Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 1Centaurin-Delta-2Cnt-D2 |
| Database Links | Reactome: R-HSA-8849469Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
| Cellular Localisation | CytoplasmGolgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCell MembraneAssociated With Golgi Stacks In Resting CellsThroughout The Cytoplasm And In Surface Protrusion In Cells That Are In The Process Of Attaching To A Surface And Spreading |
| Alternative Antibody Names | Anti-Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 1 antibodyAnti-Centaurin-Delta-2 antibodyAnti-Cnt-D2 antibodyAnti-ARAP1 antibodyAnti-CENTD2 antibodyAnti-KIAA0782 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
