Anti-CENPB antibody (STJA0009781)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CENPB
General Information
| Short Description | Rabbit polyclonal anti-Major centromere autoantigen B for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CENPB |
| Gene ID | 1059 |
| Uniprot ID | CENPB_HUMAN |
| Immunogen | Synthesized peptide derived from human CENPB |
| Specificity | This antibody detects endogenous levels of CENPB at Human, Mouse |
Additional Info
| Function | Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable). |
| Protein Name | Major Centromere Autoantigen BCentromere Protein BCenp-B |
| Database Links | |
| Cellular Localisation | NucleusChromosomeCentromere |
| Alternative Antibody Names | Anti-Major Centromere Autoantigen B antibodyAnti-Centromere Protein B antibodyAnti-Cenp-B antibodyAnti-CENPB antibody |
Information sourced from Uniprot.org