Anti-CELA2A antibody (80-150) (STJ11102876)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CELA2A (80-150) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CELA2A |
| Gene ID | 63036 |
| Uniprot ID | CEL2A_HUMAN |
| Immunogen Region | 80-150 |
| Immunogen Sequence | TYRVGLGRHNLYVAESGSLA VSVSKIVVHKDWNSNQISKG NDIALLKLANPVSLTDKIQL ACLPPAGTILP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 80-150 of human CELA2A (NP_254275.1). |
Additional Info
| Tissue Specificity | Expressed in pancreas. Not detected in keratinocytes. Detected in exocrine secretions of the pancreas (at protein level). Also expressed in a small fraction of cells in pancreatic islets, adrenal cortex, intestinal glands and colonic lymphoid follicles (at protein level). Detected in plasma. |
| Function | Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. |
| Protein Name | Chymotrypsin-Like Elastase Family Member 2aElastase-2a |
| Database Links | Reactome: R-HSA-6809371Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Chymotrypsin-Like Elastase Family Member 2a antibodyAnti-Elastase-2a antibodyAnti-CELA2A antibodyAnti-ELA2A antibody |
Information sourced from Uniprot.org