• Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CEACAM6 antibody (STJ193150)

SKU:
STJ193150

Current Stock:
Host: Rabbit
Applications: IHC/IF/WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Carcinoembryonic antigen-related cell adhesion molecule 6 is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
WB 1:500-2000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CEACAM6
Gene ID: 4680
Uniprot ID: CEAM6_HUMAN
Specificity: This antibody detects endogenous levels of human CEAM6
Immunogen: Synthesized peptide derived from the human CEAM6
Post Translational Modifications Glycosylated.
Function Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role as an oncogene by promoting tumor progression.positively regulates cell migration, cell adhesion to endothelial cells and cell invasion. Also involved in the metastatic cascade process by inducing gain resistance to anoikis of pancreatic adenocarcinoma and colorectal carcinoma cells.
Protein Name Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6
Non-Specific Crossreacting Antigen
Normal Cross-Reacting Antigen
Cd Antigen Cd66c
Database Links Reactome: R-HSA-1566977
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Antibody Names Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 antibody
Anti-Non-Specific Crossreacting Antigen antibody
Anti-Normal Cross-Reacting Antigen antibody
Anti-Cd Antigen Cd66c antibody
Anti-CEACAM6 antibody
Anti-NCA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance