Anti-CEACAM6 antibody [R06-4A5] (STJA0036485)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CEACAM6
General Information
| Short Description | Rabbit monoclonal anti-CEACAM6 for use in WB, IHC-P, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-4A5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CEACAM6 |
| Gene ID | 4680 |
| Uniprot ID | CEAM6_HUMAN |
| Immunogen | A synthesized peptide derived from human CEACAM6 |
Additional Info
| Tissue Specificity | Expressed in neutrophils. Expressed in columnar epithelial and goblet cells of the colon. Expressed in numerous tumor cell lines (at protein level). |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells. |
| Protein Name | Cell Adhesion Molecule Ceacam6Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6Cea Cell Adhesion Molecule 6Non-Specific Crossreacting AntigenNormal Cross-Reacting AntigenCd Antigen Cd66c |
| Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorApical Cell MembraneCell SurfaceLocalized To The Apical Glycocalyx Surface |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule Ceacam6 antibodyAnti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 antibodyAnti-Cea Cell Adhesion Molecule 6 antibodyAnti-Non-Specific Crossreacting Antigen antibodyAnti-Normal Cross-Reacting Antigen antibodyAnti-Cd Antigen Cd66c antibodyAnti-CEACAM6 antibodyAnti-NCA antibody |
Information sourced from Uniprot.org