Anti-CEA antibody (STJ16102837)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
ImmunogenHuman carcinoembryonic antigen (CEA; Rougier Bio-Tech code 70015)
General Information
| Short Description | Rabbit polyclonal anti-CEA for use in IHC-F and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Dilution Range | IHCFIHC-P 1:1, 000-1:5, 000 |
| Formulation | Lyophilized; reconstitute in 100 ยตl dist. water |
| Storage Instruction | Store at 2-8ยฐC for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | CEACAM5 |
| Gene ID | 1048 |
| Uniprot ID | CEAM5_HUMAN |
| Immunogen | Human carcinoembryonic antigen (CEA; Rougier Bio-Tech code 70015) |
Additional Info
| Post Translational Modifications | Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. |
| Protein Name | Cell Adhesion Molecule Ceacam5Carcinoembryonic AntigenCeaCarcinoembryonic Antigen-Related Cell Adhesion Molecule 5Cea Cell Adhesion Molecule 5Meconium Antigen 100Cd Antigen Cd66e |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorApical Cell MembraneCell SurfaceLocalized To The Apical Glycocalyx Surface |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule Ceacam5 antibodyAnti-Carcinoembryonic Antigen antibodyAnti-Cea antibodyAnti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 antibodyAnti-Cea Cell Adhesion Molecule 5 antibodyAnti-Meconium Antigen 100 antibodyAnti-Cd Antigen Cd66e antibodyAnti-CEACAM5 antibodyAnti-CEA antibody |
Information sourced from Uniprot.org