Anti-CDw78/MHC II DR antibody [IPO-10] (STJ16101042)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG3k
ImmunogenA BALB/c mouse was immunized with human B-cell line Daudi.Fusion partner: P3-X63-Ag8.653.
STJ16101042
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General Information

Short DescriptionMouse monoclonal anti-CDw78/MHC II DR for use in ELISA, FC, IF and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsELISA/FC/IF/IHC
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDIPO-10
IsotypeIgG3k
ConjugationUnconjugated
ConcentrationCan be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL.
PurificationAffinity purified from tissue culture.
Dilution RangeELISA (solid phase: 0, 1-100 ยตg/ml; tracer: 0, 001-100 ยตg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 ยตg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 ยตg/ml). Immunohistology (1-2 ยตg/ml for 30 min at RT; staining of formalin-fixed tiss
FormulationPBS with 0.02% Sodium Azide.
Storage InstructionStore for up to 1 year at 2-8ยฐC upon receipt.

Target Information

ImmunogenA BALB/c mouse was immunized with human B-cell line Daudi.Fusion partner: P3-X63-Ag8.653.

Additional Info

Background CDw78 (also called Ba antigen, Leu21 or LO panB a) is present on some immature and some mature B-cells. The antigen appears on B-cell progenitors preceding CD10, CD19, CD22 and CD37. It is expressed on resting B-cells and reappears and persists in the cytoplasm and on the cell surface until cytoplasmic Ig appears. Its expression is greatly increased after B-cell activation in vitro. It is also found on tissue macrophages and on epithelial cells, but not on Tcells, NK-cells, monocytes, granulocytes, thymocytes or bone marrow stromal fibroblasts nor myeloid tissues.

Information sourced from Uniprot.org

Citations

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