| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDS2 |
| Gene ID: | 8760 |
| Uniprot ID: | CDS2_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDS2 (NP_003809.1). |
| Immunogen Sequence: | MTELRQRVAHEPVAPPEDKE SESEAKVDGETASDSESRAE SAPLPVSADDTPEVLNRALS NLSSRWKNWWVRGILTLAMI AFFFIIIYLGPMVLMIIVMC |
| Tissue Specificity | Widely expressed. Expressed in heart, brain and retina, and to a lesser extent in placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. |
| Protein Name | Phosphatidate Cytidylyltransferase 2 Cdp-Dag Synthase 2 Cdp-Dg Synthase 2 Cdp-Diacylglycerol Synthase 2 Cds 2 Cdp-Diglyceride Pyrophosphorylase 2 Cdp-Diglyceride Synthase 2 Ctp -Phosphatidate Cytidylyltransferase 2 |
| Database Links | Reactome: R-HSA-1483148 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Phosphatidate Cytidylyltransferase 2 antibody Anti-Cdp-Dag Synthase 2 antibody Anti-Cdp-Dg Synthase 2 antibody Anti-Cdp-Diacylglycerol Synthase 2 antibody Anti-Cds 2 antibody Anti-Cdp-Diglyceride Pyrophosphorylase 2 antibody Anti-Cdp-Diglyceride Synthase 2 antibody Anti-Ctp -Phosphatidate Cytidylyltransferase 2 antibody Anti-CDS2 antibody |
Information sourced from Uniprot.org