Anti-CDKN2C antibody [R08-8Z5] (STJA0037166)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CDKN2C
STJA0037166
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General Information

Short DescriptionRabbit monoclonal anti-CDKN2C for use in WB, IHC-P, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ICC/IF/IP
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR08-8Z5
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity Purified
Dilution RangeWB 1:500-1:1000
IHC 1:50-1:100
IF 1:50-1:200
IP 1:40
FormulationRabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolCDKN2C
Gene ID1031
Uniprot IDCDN2C_HUMAN
ImmunogenA synthesized peptide derived from human CDKN2C

Additional Info

Tissue Specificity Highest levels found in skeletal muscle. Also found in pancreas and heart.
Function Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
Protein Name Cyclin-Dependent Kinase 4 Inhibitor C
Cyclin-Dependent Kinase 6 Inhibitor
P18-Ink4c
P18-Ink6
Database Links Reactome: R-HSA-2559580
Reactome: R-HSA-2559582
Reactome: R-HSA-2559585
Reactome: R-HSA-69231
Cellular Localisation
Alternative Antibody Names Anti-Cyclin-Dependent Kinase 4 Inhibitor C antibody
Anti-Cyclin-Dependent Kinase 6 Inhibitor antibody
Anti-P18-Ink4c antibody
Anti-P18-Ink6 antibody
Anti-CDKN2C antibody
Anti-CDKN6 antibody

Information sourced from Uniprot.org

Citations

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