Anti-CDKN2C antibody (3-104 aa) [R04-3C2] (STJA0011726)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human p18 INK4c
General Information
| Short Description | Rabbit monoclonal anti-CDKN2C (3-104 aa) for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-3C2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CDKN2C |
| Gene ID | 1031 |
| Uniprot ID | CDN2C_HUMAN |
| Immunogen | Recombinant protein of human p18 INK4c |
| Immunogen Region | 3-104 aa |
Additional Info
| Tissue Specificity | Highest levels found in skeletal muscle. Also found in pancreas and heart. |
| Function | Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. |
| Protein Name | Cyclin-Dependent Kinase 4 Inhibitor CCyclin-Dependent Kinase 6 InhibitorP18-Ink4cP18-Ink6 |
| Database Links | Reactome: R-HSA-2559580Reactome: R-HSA-2559582Reactome: R-HSA-2559585Reactome: R-HSA-69231 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 4 Inhibitor C antibodyAnti-Cyclin-Dependent Kinase 6 Inhibitor antibodyAnti-P18-Ink4c antibodyAnti-P18-Ink6 antibodyAnti-CDKN2C antibodyAnti-CDKN6 antibody |
Information sourced from Uniprot.org