Anti-CDK20 antibody (200-300) (STJ23053)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CDK20 (200-300) antibody for use in IHC-P and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDK20 |
| Gene ID | 23552 |
| Uniprot ID | CDK20_HUMAN |
| Immunogen Region | 200-300 |
| Immunogen Sequence | GSPLFPGKNDIEQLCYVLRI LGTPNPQVWPELTELPDYNK ISFKEQVPMPLEEVLPDVSP QALDLLGQFLLYPPHQRIAA SKALLHQYFFTAPLPAHPSE L |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CDK20 (Q8IZL9). |
Additional Info
| Function | Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling. Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'. |
| Protein Name | Cyclin-Dependent Kinase 20Cdk-Activating Kinase P42Cak-Kinase P42Cell Cycle-Related KinaseCell Division Protein Kinase 20Cyclin-Dependent Protein Kinase HCyclin-Kinase-Activating Kinase P42 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCell ProjectionCilium |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 20 antibodyAnti-Cdk-Activating Kinase P42 antibodyAnti-Cak-Kinase P42 antibodyAnti-Cell Cycle-Related Kinase antibodyAnti-Cell Division Protein Kinase 20 antibodyAnti-Cyclin-Dependent Protein Kinase H antibodyAnti-Cyclin-Kinase-Activating Kinase P42 antibodyAnti-CDK20 antibodyAnti-CCRK antibodyAnti-CDCH antibody |
Information sourced from Uniprot.org