Anti-CDK13 antibody (650-730 aa) (STJ191674)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 650-730
General Information
| Short Description | Rabbit polyclonal anti-Cyclin-dependent kinase 13 (650-730 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDK13 |
| Gene ID | 8621 |
| Uniprot ID | CDK13_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 650-730 |
| Immunogen Region | 650-730 aa |
| Specificity | CDK13 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef. |
| Protein Name | Cyclin-Dependent Kinase 13Cdc2-Related Protein Kinase 5Cell Division Cycle 2-Like Protein Kinase 5Cell Division Protein Kinase 13Hcdk13Cholinesterase-Related Cell Division Controller |
| Database Links | Reactome: R-HSA-6796648Reactome: R-HSA-6798695 |
| Cellular Localisation | Nucleus Speckle |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 13 antibodyAnti-Cdc2-Related Protein Kinase 5 antibodyAnti-Cell Division Cycle 2-Like Protein Kinase 5 antibodyAnti-Cell Division Protein Kinase 13 antibodyAnti-Hcdk13 antibodyAnti-Cholinesterase-Related Cell Division Controller antibodyAnti-CDK13 antibodyAnti-CDC2L antibodyAnti-CDC2L5 antibodyAnti-CHED antibodyAnti-KIAA1791 antibody |
Information sourced from Uniprot.org