Anti-CDHR2 antibody (STJA0008007)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PCDH24
General Information
| Short Description | Rabbit polyclonal anti-Cadherin-related family member 2 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDHR2 |
| Gene ID | 54825 |
| Uniprot ID | CDHR2_HUMAN |
| Immunogen | Synthesized peptide derived from human PCDH24 |
| Specificity | This antibody detects endogenous levels of PCDH24 at Human |
Additional Info
| Function | Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells. |
| Protein Name | Cadherin-Related Family Member 2Protocadherin LkcPc-LkcProtocadherin-24 |
| Database Links | |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillus MembraneCell Junction |
| Alternative Antibody Names | Anti-Cadherin-Related Family Member 2 antibodyAnti-Protocadherin Lkc antibodyAnti-Pc-Lkc antibodyAnti-Protocadherin-24 antibodyAnti-CDHR2 antibodyAnti-PCDH24 antibodyAnti-PCLKC antibody |
Information sourced from Uniprot.org