Anti-CDH6 antibody (1-250) (STJ110408)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CDH6 (1-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDH6 |
| Gene ID | 1004 |
| Uniprot ID | CADH6_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MRTYRYFLLLFWVGQPYPTL STPLSKRTSGFPAKKRALEL SGNSKNELNRSKRSWMWNQF FLLEEYTGSDYQYVGKLHSD QDRGDGSLKYILSGDGAGDL FIINENTGDIQATKRLDREE KPVYILRAQAINRRTGRPVE PESEFIIKIHDINDNEPIFT KEVYTATVPEMSDVGTFVVQ VTATDADDPTYGNSAKVVYS ILQGQPYFSVESETGIIKTA LLNMDRENREQYQVVIQAK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human K-Cadherin (K-Cadherin (CDH6) ) (NP_004923.1). |
Additional Info
| Tissue Specificity | Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-6Kidney CadherinK-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-6 antibodyAnti-Kidney Cadherin antibodyAnti-K-Cadherin antibodyAnti-CDH6 antibody |
Information sourced from Uniprot.org