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Anti-CDH17/Cadherin-17 nanobody [SAA0804] (STJN000013)
General Information
| Short Description | Alpaca monoclonal nanobody anti-Cadherin-17 is suitable for use in Flow Cytometry and Western Blot research applications. |
| Applications | FC/WB |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0804 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1.5 mg/mL |
| Purification | Purified by Nickel column. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4Β°C short term (1-2 weeks). Store at-20Β°C 12 months. Store at-80Β°C long term. |
Target Information
| Gene Symbol | CDH17 |
| Gene ID | 1015 |
| Uniprot ID | CAD17_HUMAN |
Additional Info
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
| Protein Name | Cadherin-17Intestinal Peptide-Associated Transporter Hpt-1Liver-Intestine CadherinLi-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Nanobody Names | Anti-Cadherin-17 nanobodyAnti-Intestinal Peptide-Associated Transporter Hpt-1 nanobodyAnti-Liver-Intestine Cadherin nanobodyAnti-Li-Cadherin nanobodyAnti-CDH17 nanobody |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Anti-CDH17/Cadherin-17 nanobody [SAA0804] (STJN000013)
This nanobody targets CDH17 (Cadherin-17, UniProt Q12864) and has confirmed reactivity against the human form of the protein. No cross-reactivity with other species has been documented in the provided product data.
This nanobody has been validated for flow cytometry (FC) and western blotting (WB). No additional applications are currently listed for this product.
This nanobody is formatted as a VHH domain with an 8xHis tag and a C-terminal Cys tag. It is supplied unconjugated, which allows researchers to apply their own labelling or conjugation strategies as needed.
This nanobody is purified by nickel affinity column chromatography, consistent with its 8xHis tag format. Purity is greater than 95% as determined by SDS-PAGE.
For short-term use of 1 to 2 weeks, this nanobody can be stored at 4Β°C. For storage up to 12 months, keep at -20Β°C, and for long-term storage beyond that, store at -80Β°C. Repeated freeze-thaw cycles should be avoided, and a manual defrost freezer is recommended.
This nanobody is supplied at a concentration of 1.5 mg/mL. No specific working dilution ranges are listed, so researchers should determine optimal concentrations empirically for their application.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.