Anti-CDH13/H-cadherin antibody (Internal) (STJ73464)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CDH13/H-cadherin (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 110kDa band observed in Human Heart lysates and 85kDa in Human Brain (Amygdala and Hippocampus) lysates (calculated MW of 78.3kDa according to NP_001248.1). The observed molecula |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CDH13 |
| Gene ID | 1012 |
| Uniprot ID | CAD13_HUMAN |
| Accession Number | NP_001248.1; NP_001207417.1; NP_001207418.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | DSDRPERSKFRLTGK |
| Specificity | The immunizing peptide represents the N terminus of the mature protein. This antibody is expected to recognize isoform 1, 2 and 3 (NP_001248.1; NP_001207417.1; NP_001207418.1). |
Additional Info
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. |
| Protein Name | Cadherin-13Heart CadherinH-CadherinP105Truncated CadherinT-CadT-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCytoplasm |
| Alternative Antibody Names | Anti-Cadherin-13 antibodyAnti-Heart Cadherin antibodyAnti-H-Cadherin antibodyAnti-P105 antibodyAnti-Truncated Cadherin antibodyAnti-T-Cad antibodyAnti-T-Cadherin antibodyAnti-CDH13 antibodyAnti-CDHH antibody |
Information sourced from Uniprot.org