Anti-CDEP/FARP1 antibody (N-Term) (STJ70446)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CDEP/FARP1 (N-Term) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/IF/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments showed an approx 110-120kDa band in Human Frontal Cortex lysates (calculated MW of 119kDa according to NP_ 005757.1).. An additional band was also consistently |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | FARP1 |
| Gene ID | 10160 |
| Uniprot ID | FARP1_HUMAN |
| Accession Number | NP_005757.1; NP_001001715.2; NP_001273768.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | GEIEQRPTPGSRL |
Additional Info
| Function | Functions as a guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses. |
| Protein Name | Ferm - Arhgef And Pleckstrin Domain-Containing Protein 1Chondrocyte-Derived Ezrin-Like ProteinFerm - Rhogef And Pleckstrin Domain-Containing Protein 1Pleckstrin Homology Domain-Containing Family C Member 2Ph Domain-Containing Family C Member 2 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9035034 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideSynapseSynaptosomeCytoplasmCytosolCell ProjectionFilopodiumDendriteDendritic SpineRecruited To The Cell Membrane Via Interaction With Cadm1 |
| Alternative Antibody Names | Anti-Ferm - Arhgef And Pleckstrin Domain-Containing Protein 1 antibodyAnti-Chondrocyte-Derived Ezrin-Like Protein antibodyAnti-Ferm - Rhogef And Pleckstrin Domain-Containing Protein 1 antibodyAnti-Pleckstrin Homology Domain-Containing Family C Member 2 antibodyAnti-Ph Domain-Containing Family C Member 2 antibodyAnti-FARP1 antibodyAnti-CDEP antibodyAnti-PLEKHC2 antibody |
Information sourced from Uniprot.org