Anti-CDCA8 antibody (STJ190614)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Borealin for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDCA8 |
| Gene ID | 55143 |
| Uniprot ID | BOREA_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | BOREA Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. |
| Protein Name | BorealinCell Division Cycle-Associated Protein 8Dasra-BHdasra-BPluripotent Embryonic Stem Cell-Related Gene 3 Protein |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-4615885Reactome: R-HSA-5663220Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusNucleolusCytoplasmCytoskeletonSpindleChromosomeCentromereLocalizes On Chromosome Arms And Inner Centromeres From Prophase Through Metaphase And Then Transferring To The Spindle Midzone And Midbody From Anaphase Through CytokinesisColocalizes With Senp3 In The Nucleolus In Interphase Cells |
| Alternative Antibody Names | Anti-Borealin antibodyAnti-Cell Division Cycle-Associated Protein 8 antibodyAnti-Dasra-B antibodyAnti-Hdasra-B antibodyAnti-Pluripotent Embryonic Stem Cell-Related Gene 3 Protein antibodyAnti-CDCA8 antibodyAnti-PESCRG3 antibody |
Information sourced from Uniprot.org