Anti-CDCA7L antibody (140-220 aa) (STJ190277)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 140-220
General Information
| Short Description | Rabbit polyclonal anti-Cell division cycle-associated 7-like protein (140-220 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDCA7L |
| Gene ID | 55536 |
| Uniprot ID | CDA7L_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 140-220 |
| Immunogen Region | 140-220 aa |
| Specificity | CDA7L Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylation increases its interaction with PSIP1. |
| Function | Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways.May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. |
| Protein Name | Cell Division Cycle-Associated 7-Like ProteinProtein Jpo2Transcription Factor Ram2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusAssociates With ChromatinTranslocates From Cytoplasm To Nucleus Under Dexamethasone Induction |
| Alternative Antibody Names | Anti-Cell Division Cycle-Associated 7-Like Protein antibodyAnti-Protein Jpo2 antibodyAnti-Transcription Factor Ram2 antibodyAnti-CDCA7L antibodyAnti-HR1 antibodyAnti-JPO2 antibodyAnti-R1 antibody |
Information sourced from Uniprot.org