Anti-CDCA7 antibody (141-190 aa) (STJ92186)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CDCA7 at the amino acid range 141-190
General Information
| Short Description | Rabbit polyclonal anti-Cell division cycle-associated protein 7 (141-190 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDCA7 |
| Gene ID | 83879 |
| Uniprot ID | CDCA7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CDCA7 at the amino acid range 141-190 |
| Immunogen Region | 141-190 aa |
| Specificity | CdcA7 Polyclonal Antibody detects endogenous levels of CdcA7 protein. |
Additional Info
| Post Translational Modifications | Phosphorylation at Thr-163 promotes interaction with YWHAE and YWHAZ, dissociation from MYC and sequestration in the cytoplasm. In vitro, phosphorylated at Thr-163 by AKT. |
| Function | Participates in MYC-mediated cell transformation and apoptosis.induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator. |
| Protein Name | Cell Division Cycle-Associated Protein 7Protein Jpo1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmPredominantly Nuclear With Some Expression Also Seen In The CytoplasmPredominantly Cytoplasmic When Phosphorylated At Thr-163 |
| Alternative Antibody Names | Anti-Cell Division Cycle-Associated Protein 7 antibodyAnti-Protein Jpo1 antibodyAnti-CDCA7 antibodyAnti-JPO1 antibody |
Information sourced from Uniprot.org