| Short Description : | Rabbit monoclonal Cdc37 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S9MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDC37 |
| Gene ID: | 11140 |
| Uniprot ID: | CDC37_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MVDYSVWDHIEVSDDEDETH PNIDTASLFRWRHQARVERM EQFQKEKEELDRGCRECKRK VAECQRKLKELEVAEGGKAE LERLQAEAQQLRKEERSWEQ |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC37 (Q16543). |
| Post Translational Modifications | Constitutively sumoylated by UBE2I. |
| Function | Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity. |
| Protein Name | Hsp90 Co-Chaperone Cdc37Hsp90 Chaperone Protein Kinase-Targeting SubunitP50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-1227986Reactome: R-HSA-1236382Reactome: R-HSA-5637810Reactome: R-HSA-5675482Reactome: R-HSA-8863795Reactome: R-HSA-9013418Reactome: R-HSA-9634285Reactome: R-HSA-9652282Reactome: R-HSA-9664565Reactome: R-HSA-9665233Reactome: R-HSA-9665244Reactome: R-HSA-9665245Reactome: R-HSA-9665246Reactome: R-HSA-9665247Reactome: R-HSA-9665249Reactome: R-HSA-9665250Reactome: R-HSA-9665251Reactome: R-HSA-9665348Reactome: R-HSA-9665686Reactome: R-HSA-9665737 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Hsp90 Co-Chaperone Cdc37 antibodyAnti-Hsp90 Chaperone Protein Kinase-Targeting Subunit antibodyAnti-P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed antibodyAnti-CDC37 antibodyAnti-CDC37A antibody |
Information sourced from Uniprot.org
