Anti-CDC25 antibody [R06-5H5] (STJA0034150)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human CDC25
General Information
| Short Description | Rabbit monoclonal anti-CDC25 for use in WB in Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-5H5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | RASGRF1 |
| Gene ID | 5923 |
| Uniprot ID | RGRF1_HUMAN |
| Immunogen | A synthetic peptide of human CDC25 |
Additional Info
| Post Translational Modifications | Phosphorylated by PLK2, leading to ubiquitination and degradation by the proteasome. Ubiquitinated and degraded following phosphorylation by PLK2. Phosphorylated by SRC and LCK. Phosphorylation by LCK increases its capacity to stimulate the GDP/GTP exchange on Ras, whereas its phosphorylation by SRC seems not to have an effect on stimulation activity. |
| Function | Promotes the exchange of Ras-bound GDP by GTP. |
| Protein Name | Ras-Specific Guanine Nucleotide-Releasing Factor 1Ras-Grf1Guanine Nucleotide-Releasing ProteinGnrpRas-Specific Nucleotide Exchange Factor Cdc25 |
| Database Links | Reactome: R-HSA-442982Reactome: R-HSA-5673001 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ras-Specific Guanine Nucleotide-Releasing Factor 1 antibodyAnti-Ras-Grf1 antibodyAnti-Guanine Nucleotide-Releasing Protein antibodyAnti-Gnrp antibodyAnti-Ras-Specific Nucleotide Exchange Factor Cdc25 antibodyAnti-RASGRF1 antibodyAnti-CDC25 antibodyAnti-GNRP antibodyAnti-GRF1 antibody |
Information sourced from Uniprot.org