| Short Description : | Rabbit polyclonal CD99 (23-185) antibody for use in WB, IHC-P, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD99 |
| Gene ID: | 4267 |
| Uniprot ID: | CD99_HUMAN |
| Immunogen Region: | 23-185 |
| Immunogen Sequence: | DGGFDLSDALPDNENKKPTA IPKKPSAGDDFDLGDAVVDG ENDDPRPPNPPKPMPNPNPN HPSSSGSFSDADLADGVSGG EGKGGSDGGGSHRKEGEEAD APGVIPGIVGAVVVAVAGAI SSFIAYQKKKLCFKENAEQG EVDMESHRNANAEPAVQRTL LEK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-185 of human CD99 (NP_002405.1). |
| Post Translational Modifications | Extensively O-glycosylated. |
| Function | Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes. |
| Protein Name | Cd99 Antigen12e7E2 AntigenProtein Mic2T-Cell Surface Glycoprotein E2Cd Antigen Cd99 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-202733 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd99 Antigen antibodyAnti-12e7 antibodyAnti-E2 Antigen antibodyAnti-Protein Mic2 antibodyAnti-T-Cell Surface Glycoprotein E2 antibodyAnti-Cd Antigen Cd99 antibodyAnti-CD99 antibodyAnti-MIC2 antibodyAnti-MIC2X antibodyAnti-MIC2Y antibody |
Information sourced from Uniprot.org
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