Anti-CD97 antibody (24-265 aa) (STJ11105186)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CD97 (24-265 aa) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Adgre5 |
| Gene ID | 26364 |
| Uniprot ID | AGRE5_MOUSE |
| Immunogen Region | 24-265 aa |
| Immunogen Sequence | QKAESKNCAKWCPINSKCVS NRSCVCKPGFSSEKELITNP AESCEDINECLLPGFSCGDF AMCKNSEGSYTCVCNLGYKL LSGAESFVNESENTCQASVN TGMTPVPSRIHTVTTAPGNL PEQTTTVHQTQMGDSEERTP KDVNECISGQNHCHQSTHCI NKLGGYSCICRQGWKPVPGS PNGPVSTVCEDVDECSSGQH QCHNSTVCKNTVGSYKCHCR PGWKPTSGSLRGPDTICQE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-265 of mouse CD97. (NP_036055.2). |
Additional Info
| Tissue Specificity | Although predominantly expressed by cells of the immune system, expressed ubiquitously with particularly high levels of expression in the lung and the thymus gland. In the spleen, expression is detected on most myeloid cells and variable portions of T-cells, B-cells and NK cells. In the bone marrow, expressed in nearly all myeloid cells, whereas little if any expression is found on erythroid cells. |
| Post Translational Modifications | Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. |
| Function | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. |
| Protein Name | Adhesion G Protein-Coupled Receptor E5Leukocyte Antigen Cd97Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta |
| Database Links | Reactome: R-MMU-373080Reactome: -MMU-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinAdhesion G Protein-Coupled Receptor E5 Subunit Alpha: SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E5 antibodyAnti-Leukocyte Antigen Cd97 antibodyAnti-Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta antibodyAnti-Adgre5 antibodyAnti-Cd97 antibody |
Information sourced from Uniprot.org