Anti-CD96 antibody (C-Term) (STJ73086)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CD96 (C-Term) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments gave an approx 100+75kDa bands in Jurkat lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature f |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CD96 |
| Gene ID | 10225 |
| Uniprot ID | TACT_HUMAN |
| Accession Number | NP_937839.1; NP_005807.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | KYTCIQEPNESD |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_937839.1; NP_005807.1). |
Additional Info
| Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
| Protein Name | T-Cell Surface Protein TactileCell Surface Antigen Cd96T Cell-Activated Increased Late Expression ProteinCd Antigen Cd96 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Surface Protein Tactile antibodyAnti-Cell Surface Antigen Cd96 antibodyAnti-T Cell-Activated Increased Late Expression Protein antibodyAnti-Cd Antigen Cd96 antibodyAnti-CD96 antibody |
Information sourced from Uniprot.org