Anti-CD96 antibody (270-370) (STJ11103987)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal T-Cell Surface Protein Tactile (270-370) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD96 |
| Gene ID | 10225 |
| Uniprot ID | TACT_HUMAN |
| Immunogen Region | 270-370 |
| Immunogen Sequence | EIPVIVENNSTDVLVERRFT CLLKNVFPKANITWFIDGSF LHDEKEGIYITNEERKGKDG FLELKSVLTRVHSNKPAQSD NLTIWCMALSPVPGNKVWNI S |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 270-370 of human CD96 (NP_937839.1). |
Additional Info
| Tissue Specificity | Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells. |
| Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
| Protein Name | T-Cell Surface Protein TactileCell Surface Antigen Cd96T Cell-Activated Increased Late Expression ProteinCd Antigen Cd96 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Surface Protein Tactile antibodyAnti-Cell Surface Antigen Cd96 antibodyAnti-T Cell-Activated Increased Late Expression Protein antibodyAnti-Cd Antigen Cd96 antibodyAnti-CD96 antibody |
Information sourced from Uniprot.org