Anti-CD89 antibody {ABflo® 488} (STJ11108517)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationABflo® 488
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal CD89 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | ABflo® 488 |
| Purification | Affinity purification |
| Dilution Range | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | FCAR |
| Gene ID | 2204 |
| Uniprot ID | FCAR_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages.however only one isoform is expressed at alveolar macrophages surfaces. |
| Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. |
| Protein Name | Immunoglobulin Alpha Fc ReceptorIga Fc ReceptorCd Antigen Cd89 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform A1: Cell MembraneSingle-Pass Type I Membrane Protein2: Cell Membrane3: Cell MembraneIsoform B: SecretedIsoform B-Delta-S2: Secreted |
| Alternative Antibody Names | Anti-Immunoglobulin Alpha Fc Receptor antibodyAnti-Iga Fc Receptor antibodyAnti-Cd Antigen Cd89 antibodyAnti-FCAR antibodyAnti-CD89 antibody |
Information sourced from Uniprot.org