Anti-CD87/PLAUR/uPAR antibody [SAA2029] {APC} (STJA0029517)

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STJA0029517-100
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Short Description :Mouse monoclonal Urokinase Plasminogen Activator Surface Receptor antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA2029
Isotype:IgG1k
Conjugation:APC
Concentration:0.5 mg/mL
Purification:Purified
Formulation:PBS pH 7.4, 50% glycerol, 0.05% proclin300
Storage Instruction:Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol:PLAUR
Gene ID:5329
Uniprot ID:UPAR_HUMAN
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Protein Name Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87
Database Links Reactome: R-HSA-162791
Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin- And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Antibody Names Anti-Urokinase Plasminogen Activator Surface Receptor antibody
Anti-U-Par antibody
Anti-Upar antibody
Anti-Monocyte Activation Antigen Mo3 antibody
Anti-Cd Antigen Cd87 antibody
Anti-PLAUR antibody
Anti-MO3 antibody
Anti-UPAR antibody

Information sourced from Uniprot.org