• Western blot analysis of various lysates, using CD80 Rabbit monoclonal antibody antibody (STJ11105144) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-CD80 antibody [S5144RM] (STJ11105144)

SKU:
STJ11105144

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-T-Lymphocyte Activation antigen Cd80 is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S5144RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD80
Gene ID: 941
Uniprot ID: CD80_HUMAN
Immunogen: Recombinant protein of human CD80.
Tissue Specificity Expressed on activated B-cells, macrophages and dendritic cells.
Function Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Protein Name T-Lymphocyte Activation Antigen Cd80
Activation B7-1 Antigen
Bb1
Ctla-4 Counter-Receptor B7.1
B7
Cd Antigen Cd80
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-389356
Reactome: R-HSA-389357
Reactome: R-HSA-389359
Reactome: R-HSA-389513
Reactome: R-HSA-6783783
Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-T-Lymphocyte Activation Antigen Cd80 antibody
Anti-Activation B7-1 Antigen antibody
Anti-Bb1 antibody
Anti-Ctla-4 Counter-Receptor B7.1 antibody
Anti-B7 antibody
Anti-Cd Antigen Cd80 antibody
Anti-CD80 antibody
Anti-CD28LG antibody
Anti-CD28LG1 antibody
Anti-LAB7 antibody

Information sourced from Uniprot.org

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